Phosoplex and Gout - Gout: New Treatments and Recommendations for Prevention
Gout commonly presents along with a sudden onset of redness, swelling and excruciating pain of the great toe joint during the night. Gout will be a painful joint condition due to hyperuricemia (high levels of uric acid in the blood) resulting in the actual precipitation of needle-like crystals in the joints. The prevalence of gout has been steadily increasing over the past two decades is now estimated to be 1-2% of the U.S. population. Gout is more common in men, but in recent years, the incidence of gout has doubled in women (1,2). The common causes of gout are diet, overproduction of uric acid and renal disease. Common risk factors include family history, male gender, a high protein diet, heavy alcohol consumption intake, high blood pressure, kidney disease, metabolic syndrome, diuretic make use of and obesity. Hyperuricemia has been suspected to increase the risk of heart disease by increasing inflammatory factors that damage arteries (3).
Arthritis Rheum. 2010 Jan Arch Intern Med. 2009;169( :502- Curr Rheumatol Rep. 2010 Apr;12( :118-24 Pharmacotherapy. 2010 Jun;30( :594-
Treatment Varies Regarding Acute and Chronic GoutFor acute gout flares, the standard treatment is a course of anti-inflammatory medications, steroid injections and/or joint aspiration. Allopurinol is commonly used for treatment of chronic gout and prevention of acute gout episodes. Febuxostat is a new medication recently approved by the Fda. In long term studies over a 5-year period, febuxostat was shown to reduce uric acid levels as well as substantially decrease or perhaps eliminate acute gout assaults ( . A study last year in the Antioch university new england Medicine showed 500 mg of Vitamin c each day reduced the incidence of gout by 15% ( . Some efficient natural gout remedies Research Centre of Canada in Vancouver found long-term coffee consumption is associated with a lower incidence of gout. Those who drank four + cups of coffee per day had the least risk of developing gout ( . The authors did not recommend starting to drink coffee for those those who do not already drink coffee.
The Most Effective Prevention of Gout is the Modification of Diet and LifestyleSpecific foods and beverages, which includes red meat and alcohol, can bring about a serious gout attack. Being overweight increases the risk got gout and other conditions which increase the risk of gout, such as bring about as well as metabolic syndrome. Weight reduction and also daily exercise are both appropriate preventative remedies for gout. Other recommendations include limiting intake of sugary beverages and foods with added sugar, consuming whole grain products, lutz, dried beans, many fruits, greens, moderate amounts of lean white meats and also low fat milk and oily fish ( . Gout medicine otc talk to your doctor about adding a vitamin c supplement or increasing your coffee intake. The development of Uric Acid has been explained in detail in this article on Uric Acid. Read it to find something interesting and surprising!
The relationship between heart disease and gout has been thought in order to be more coincidental than causative, till recently. Recent research suggests uric acid may be a causative factor in heart disease. Uric acid activates the immune response and the inflammatory process. This reaction can be seen in an acute gout flare involving an unpleasant, red, hot, swollen great toe joint. Uric acid is both an antioxidant and a pro-oxidant. This means that although uric acid may quench free radicals and reduce oxidative cell damage, it also increases mediators which damage blood vessels and increase the risk of heart disease ( . Producing such an interesting anecdote on Uric took a lot of time and hard work. So it would be enhancing to us to learn that you have made good use of this hard work!